CRISPR
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Space Diagnostics
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MISSIONS
RESEARCH EXPLORER
PUBLICATIONS
Life Science
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Space Diagnostics (Ax-1 CRISPR) tests CRISPR-based genetic identification on the Axiom-1 (Ax-1) private astronaut mission (PAM). CRISPR is a genome editing system that allows its users to detect and manipulate specific DNA and RNA sequences in living cells of diverse species. This technology could provide rapid and accurate detection of pathogens and contaminants on future long-term space missions.
PUBLICATION
CRISPR-based genetic diagnostics in microgravity
- CRISPR-based genetic diagnostics was successfully used in microgravity
- Coupling Cas12a collateral activity with recombinase polymerase amplification (RPA) detected DNA in attomolar concentrations.
- Detection stability was maintained following deep freeze long-term storage and thus could be used for long space missions.
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